Phillies vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for April 6

Odds updated as of 7:22 a.m.

The Philadelphia Phillies will face the San Francisco Giants in MLB action on Monday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Phillies vs Giants Game Info

• Philadelphia Phillies (5-4) vs. San Francisco Giants (3-7)
• Date: Monday, April 6, 2026
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and NBCS-PH+

Phillies vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-116) | SF: (-102)
• Spread: PHI: -1.5 (+155) | SF: +1.5 (-188)
• Total: 8 -- Over: (-105) | Under: (-115)

Phillies vs Giants Probable Starting Pitchers

Probable Pitchers: Andrew Painter (Phillies) - 1-0, 1.69 ERA vs Adrian Houser (Giants) - 0-1, 1.69 ERA

The Phillies will give the nod to Andrew Painter (1-0) against the Giants and Adrian Houser (0-1). Painter and his team failed to cover the spread in his only opportunity this season as a starter. Painter's team won his only start as a favorite this season. Houser has started only one game with a set spread, which the Giants failed to cover. The Giants were the moneyline underdog for one Houser start this season -- they lost.

Phillies vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (51%)

Phillies vs Giants Moneyline

• The moneyline numbers for Phillies vs. Giants reveal Philadelphia as the favorite (-116) and San Francisco as the underdog (-102) despite being the home team.

Phillies vs Giants Spread

• The Giants are +1.5 on the spread (-188 to cover), and Philadelphia is +155 to cover the runline.

Phillies vs Giants Over/Under

• The Phillies-Giants game on April 6 has been given an over/under of 8 runs. The over is set at -105 and the under at -115.

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Phillies vs Giants Betting Trends

• The Phillies have been chosen as favorites in nine games this year and have walked away with the win five times (55.6%) in those games.
• Philadelphia has a record of 5-4 when favored by -116 or more this year.
• The Phillies and their opponents have gone over in five of their nine games with a total set by sportsbooks this season.
• The Phillies are 2-7-0 against the spread in their nine games that had a posted line this season.
• The Giants have won two of the seven games they were listed as the moneyline underdog this season (28.6%).
• San Francisco is 2-5 (winning just 28.6% of its games) when it has played as a moneyline underdog of -102 or longer.
• The Giants have played in 10 games with a set over/under, and have combined with opponents to go over the total four times (4-3-3).
• The Giants have covered just 20% of their games this season, going 2-8-0 ATS.

Phillies Player Leaders

• Brandon Marsh has three doubles, a home run and two walks while hitting .303. He has an on-base percentage of .343 and a slugging percentage of .485.
• Among all qualifying hitters in baseball, he ranks 36th in batting average, 75th in on-base percentage, and 49th in slugging.
• Marsh hopes to build on a six-game hitting streak in this matchup. During his last nine outings he is hitting .303 with three doubles, a home run, two walks and five RBIs.
• Trea Turner has an OPS of .736, fueled by an OBP of .341 and a team-best slugging percentage of .395 this season. He's batting .289.
• He ranks 50th in batting average, 78th in on-base percentage and 86th in slugging among qualified hitters.
• Turner heads into this game looking to extend his six-game hit streak. During his last nine games he is batting .289 with four doubles, three walks and two RBIs.
• Kyle Schwarber has six hits and an OBP of .366, both of which lead the Phillies this season.
• Alec Bohm has been key for Philadelphia with six hits, an OBP of .282 plus a slugging percentage of .265.
• Bohm has safely hit in three games in a row. In his last five games he is batting .200 with two walks and three RBIs.

Giants Player Leaders

• Matt Chapman has put up an on-base percentage of .310 and has nine hits, both team-best numbers for the Giants. He's batting .237 and slugging .368.
• Including all qualified players in MLB, his batting average puts him 89th, his on-base percentage ranks 106th, and he is 100th in slugging.
• Luis Arraez's .350 slugging percentage paces his team. He has a batting average of .275 with an on-base percentage of .286.
• He is currently 59th in batting average, 132nd in on-base percentage and 112th in slugging percentage among all qualifying hitters.
• Jung Hoo Lee is hitting .152 with three doubles and five walks.
• Rafael Devers is batting .211 with a double, a home run and four walks.

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