Orioles vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 7

Odds updated as of 9:12 p.m.

The Baltimore Orioles will take on the Chicago White Sox in MLB action on Tuesday.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Orioles vs White Sox Game Info

• Baltimore Orioles (3-6) vs. Chicago White Sox (4-5)
• Date: Tuesday, April 7, 2026
• Time: 3:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN+ and MASN

Orioles vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-138) | CHW: (+118)
• Spread: BAL: -1.5 (+128) | CHW: +1.5 (-154)
• Total: 7 -- Over: (-105) | Under: (-115)

Orioles vs White Sox Probable Starting Pitchers

Probable Pitchers: Trevor Rogers (Orioles) - 2-0, 1.38 ERA vs Shane Smith (White Sox) - 0-2, 19.29 ERA

The Orioles will give the ball to Trevor Rogers (2-0, 1.38 ERA), who is eyeing win No. 3 on the season, and the White Sox will counter with Shane Smith (0-2, 19.29 ERA). Rogers has a record of 1-1-0 ATS in two starts with a spread this season. Rogers' team is 2-0 this season when he starts and they're favored on the moneyline. Smith has started two games with set spreads, and the White Sox failed to cover in both chances. The White Sox were the underdog on the moneyline for two Smith starts this season -- they lost both.

Orioles vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (50.9%)

Orioles vs White Sox Moneyline

• The moneyline numbers for Orioles vs. White Sox reveal Baltimore as the favorite (-138) and Chicago as the underdog (+118) despite being the home team.

Orioles vs White Sox Spread

• The Orioles are 1.5-run road favorites on the runline against the White Sox. The Orioles are +128 to cover, and the White Sox are -154.

Orioles vs White Sox Over/Under

• The Orioles-White Sox contest on April 7 has been given an over/under of 7 runs. The over is set at -105 and the under at -115.

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Orioles vs White Sox Betting Trends

• The Orioles have been victorious in three of the six contests they have been chosen as favorites in this season.
• This season Baltimore has been victorious two times in three chances when named as a favorite of at least -138 on the moneyline.
• The Orioles and their opponents have hit the over in five of their nine games with a total set by oddsmakers this season.
• The Orioles are 2-7-0 against the spread in their nine games that had a posted line this season.
• The White Sox have won 44.4% of the games this season they were the underdog on the moneyline (4-5).
• Chicago is 4-5 (winning 44.4% of its games) when it has played as a moneyline underdog of +118 or longer.
• The White Sox have combined with opponents to hit the over on the total seven times this season for a 7-2-0 record against the over/under.
• The White Sox have covered 44.4% of their games this season, going 4-5-0 ATS.

Orioles Player Leaders

• Gunnar Henderson is hitting .216 with two doubles, two home runs and four walks. He has an on-base percentage of .310 and a slugging percentage of .432.
• Among qualifying hitters in MLB, he ranks 120th in batting average, 108th in on-base percentage, and 72nd in slugging.
• Taylor Ward has 12 hits and an OBP of .429 to go with a slugging percentage of .457. All three of those stats are tops among Baltimore hitters this season. He's batting .343.
• Among qualifying hitters, his batting average ranks him 20th, his on-base percentage 18th, and his slugging percentage 65th.
• Adley Rutschman is batting .333 with a .524 slugging percentage and two RBI this year.
• Rutschman heads into this matchup with two games in a row with at least one hit. During his last five outings he is hitting .333 with three doubles, two walks and two RBIs.
• Dylan Beavers has been key for Baltimore with eight hits, an OBP of .308 plus a slugging percentage of .462.
• Beavers takes a four-game hitting streak into this matchup. During his last five outings he is hitting .350 with a home run and two RBIs.

White Sox Player Leaders

• Miguel Vargas has a team-high OBP (.389) and slugging percentage (.552). He's batting .276.
• He ranks 56th in batting average, 36th in on-base percentage and 33rd in slugging percentage among all qualified batters in the majors.
• Munetaka Murakami's seven hits lead his team. He has a batting average of .226 while slugging .613 with an on-base percentage of .342.
• Including all qualified players, he is 108th in batting average, 78th in on-base percentage and 18th in slugging percentage.
• Colson Montgomery has two home runs and four walks while batting .226.
• Chase Meidroth is hitting .200 with two doubles, a home run and four walks.

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