Ole Miss vs Tulane Prediction, Odds, Picks, Best Bets for 2025 CFP First Round

Saturday's slate in college football includes a matchup between the Ole Miss Rebels and the Tulane Green Wave.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Ole Miss vs Tulane Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ole Miss: (-901) | Tulane: (+610)
• Spread: Ole Miss: -17.5 (-104) | Tulane: +17.5 (-118)
• Total: 56.5 -- Over: (-112) | Under: (-108)

Ole Miss vs Tulane Betting Trends

• Ole Miss is 7-5-0 against the spread this year.
• Ole Miss owns one win ATS (1-2) as a 17.5-point favorite or greater this season.
• This season, six of Ole Miss' 12 games have hit the over.
• Tulane has seven wins in 13 contests against the spread this year.
• Of 13 Tulane games so far this season, four have hit the over.

Ole Miss vs Tulane Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Rebels win (86.5%)

Ole Miss vs Tulane Point Spread

Tulane is the underdog by 17.5 points against Ole Miss. Tulane is -104 to cover the spread, and Ole Miss is -118.

Ole Miss vs Tulane Over/Under

The over/under for the Ole Miss versus Tulane matchup on Dec. 20 has been set at 56.5, with -112 odds on the over and -108 odds on the under.

Ole Miss vs Tulane Moneyline

The Ole Miss vs Tulane moneyline has Ole Miss as a -901 favorite, while Tulane is a +610 underdog.

Ole Miss vs. Tulane Points Insights

Ole Miss vs. Tulane Game Info

• Game day: Saturday, December 20, 2025
• Game time: 3:30 p.m. ET
• TV channel: TNT
• Location: Oxford, Mississippi
• Stadium: Vaught-Hemingway Stadium

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Check out even more in-depth Ole Miss vs. Tulane analysis on FanDuel Research.