Nationals vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for April 7

Odds updated as of 2:13 a.m.

Tuesday's slate in the MLB includes a matchup between the Washington Nationals and the St. Louis Cardinals.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Nationals vs Cardinals Game Info

• Washington Nationals (4-6) vs. St. Louis Cardinals (5-5)
• Date: Tuesday, April 7, 2026
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: Nationals.TV and Cardinals.TV

Nationals vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: WSH: (-108) | STL: (-108)
• Spread: WSH: +1.5 (-184) | STL: -1.5 (+152)
• Total: 7.5 -- Over: (-106) | Under: (-114)

Nationals vs Cardinals Probable Starting Pitchers

Probable Pitchers: Cade Cavalli (Nationals) - 0-0, 2.79 ERA vs Matthew Liberatore (Cardinals) - 0-0, 1.64 ERA

This contest's pitching matchup is set, as the Nationals will send Cade Cavalli to the mound, while Matthew Liberatore will take the ball for the Cardinals. Cavalli has a record of 2-0-0 ATS in two starts with a spread this season. This will be Cavalli's first game as the moneyline favorite this season. Liberatore has started two games with set spreads, and the Cardinals covered in both opportunities. The Cardinals were named the moneyline underdog for two Liberatore starts this season -- they won both.

Nationals vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (51.9%)

Nationals vs Cardinals Moneyline

• St. Louis is the underdog, -108 on the moneyline, while Washington is a -108 favorite at home.

Nationals vs Cardinals Spread

Nationals vs Cardinals Over/Under

• An over/under of 7.5 has been set for Nationals-Cardinals on April 7, with the over being -106 and the under -114.

Bet on Washington Nationals vs. St. Louis Cardinals on FanDuel today!

Nationals vs Cardinals Betting Trends

• The Nationals will be named as the favorite for the first time this season.
• These are the best odds of a victory sportsbooks have given Washington this season, with a -108 moneyline set for this game.
• Contests with the Nationals have gone over the total set by oddsmakers in eight of 10 chances this season.
• The Nationals are 6-4-0 against the spread in their 10 games that had a posted line this season.
• The Cardinals have won five of the nine games they were listed as the moneyline underdog this season (55.6%).
• St. Louis has a 5-4 record (winning 55.6% of its games) when playing as a moneyline underdog of -108 or longer.
• The Cardinals have combined with opponents to go over the total five times this season for a 5-4-1 record against the over/under.
• The Cardinals have gone 5-5-0 against the spread this season.

Nationals Player Leaders

• C.J. Abrams leads Washington in total hits (10) this season while batting .286 with four extra-base hits. He has an on-base percentage of .390 and a slugging percentage of .629.
• Among all qualifying batters in baseball, he is 47th in batting average, 41st in on-base percentage, and 13th in slugging.
• Abrams will look for his eighth straight game with a hit in this contest. During his last nine outings he is batting .286 with four home runs, five walks and 13 RBIs.
• Joey Wiemer is hitting .476 with a triple, two home runs and five walks. He's slugging .857 with an on-base percentage of .577.
• Luis Garcia has collected 11 base hits, an OBP of .324 and a slugging percentage of .528 this season.
• James Wood is batting .163 with a .280 OBP and nine RBI for Washington this season.
• Wood takes a two-game hitting streak into this game. During his last five outings he is batting .190 with a double, two home runs, four walks and six RBIs.

Cardinals Player Leaders

• Jordan Walker has accumulated a team-best slugging percentage (.629) while leading the Cardinals in hits (11). He's batting .314 and with an on-base percentage of .385.
• He ranks 32nd in batting average, 48th in on-base percentage and 13th in slugging percentage among all qualifying hitters in the majors.
• Walker heads into this game on a three-game hitting streak. In his last five games he is batting .333 with two home runs, a walk and six RBIs.
• Alec Burleson has two doubles, a home run and seven walks while hitting .216. He's slugging .351 with an on-base percentage of .333.
• He is 115th in batting average, 83rd in on-base percentage and 116th in slugging percentage in the big leagues.
• JJ Wetherholt a has .386 on-base percentage to pace the Cardinals.
• Ivan Herrera is hitting .200 with three doubles and eight walks.

Nationals vs Cardinals Head to Head

• 4/6/2026: 9-6 WSH (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/10/2025: 8-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/9/2025: 8-2 WSH (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/11/2025: 6-1 STL (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/10/2025: 4-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/9/2025: 10-0 STL (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 7/28/2024: 4-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/27/2024: 14-3 WSH (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/26/2024: 10-8 WSH (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 7/8/2024: 6-0 STL (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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