Lakers vs. Celtics Prediction, Odds, Picks, Best Bets for Feb. 22

Lakers vs. Celtics Game Info

• Date: Sunday, February 22, 2026
• Time: 6:30 p.m. ET
• Venue: Crypto.com Arena -- Los Angeles, California
• Coverage: NBC/Peacock

Two of the league's top scorers square off when Jaylen Brown (fourth, 29.2 PPG) and the Boston Celtics (36-19) visit Luka Doncic (first, 33 PPG) and the Los Angeles Lakers (34-21) on Sunday, February 22, 2026 at 6:30 p.m. ET on NBC/Peacock. The Celtics are 1.5-point favorites. The matchup has an over/under set at 228.5 points.

Lakers vs. Celtics Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Lakers vs. Celtics Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Celtics win (55.2%)

Lakers vs. Celtics Betting Trends

• The Celtics have covered the spread 31 times over 55 games with a set spread.
• The Lakers are 29-25-1 against the spread this year.
• Celtics games have gone over the total 21 times this season.
• The Lakers have eclipsed the over/under 56.4% of the time this year (31 of 55 games with a set point total).
• Boston has done a better job covering the spread in road games (18-9-1) than it has in home games (13-14-0).
• The Celtics have gone over the total in 10 of 27 home games (37%). They've fared better in road games, going over the total in 11 of 28 matchups (39.3%).
• Against the spread, Los Angeles has had better results away (16-13-0) than at home (13-12-1).
• In 2025-26, a higher percentage of the Lakers' games have finished above the over/under at home (69.2%, 18 of 26) than on the road (44.8%, 13 of 29).

Celtics Leaders

• Brown is averaging 29.2 points, 7 boards and 4.8 assists. At the other end, he averages 1 steal and 0.4 blocked shots.
• Derrick White's numbers on the season are 17.1 points, 4.4 rebounds and 5.6 assists per game, shooting 38.8% from the field and 32.1% from downtown, with an average of 2.8 made 3-pointers.
• Nikola Vucevic is averaging 16.5 points, 3.6 assists and 8.9 boards.
• Payton Pritchard's numbers on the season are 17.4 points, 4.2 rebounds and 5.4 assists per game, shooting 46.5% from the field and 36.1% from downtown, with an average of 2.6 made treys.
• Neemias Queta's numbers on the season are 9.7 points, 8.2 boards and 1.5 assists per game, shooting 64% from the floor (fifth in NBA).

Lakers Leaders

• Doncic averages 33 points, 7.8 rebounds and 8.6 assists. He is also sinking 47.3% of his shots from the field and 35.2% from 3-point range, with 3.7 triples per contest (first in league).
• The Lakers receive 21.7 points per game from LeBron James, plus 5.7 boards and 7.2 assists.
• The Lakers get 13.2 points per game from Deandre Ayton, plus 8.4 rebounds and 0.9 assists.
• Per game, Austin Reaves gives the Lakers 25.6 points, 5.1 boards and 5.9 assists, plus 1 steal and 0.2 blocks.
• The Lakers get 9.3 points per game from Jake LaRavia, plus 4 rebounds and 1.9 assists.

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