Heat vs. Grizzlies Prediction, Odds, Picks, Best Bets for Feb. 21

Heat vs. Grizzlies Game Info

• Date: Saturday, February 21, 2026
• Time: 8 p.m. ET
• Venue: Kaseya Center -- Miami, Florida
• Coverage: FDSSUN, FDSSE, and WPLG

The Memphis Grizzlies (21-33) are heavy underdogs (-11.5) as they try to break a four-game road losing streak when they take on the Miami Heat (30-27) on Saturday, February 21, 2026 at Kaseya Center. The contest airs at 8 p.m. ET on FDSSUN, FDSSE, and WPLG. The matchup has an over/under set at 236.5 points.

Heat vs. Grizzlies Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Heat vs. Grizzlies Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Heat win (69.1%)

Heat vs. Grizzlies Betting Trends

• The Heat are 33-23-1 against the spread this season.
• The Grizzlies have played 54 games, with 25 wins against the spread.
• This season, 29 of the Heat's games have gone over the point total out of 54 chances.
• Grizzlies games this season have hit the over on 25 of 54 set point totals (46.3%).
• Miami has done a better job covering the spread when playing on the road (19-10-1) than it has in home games (14-13-0).
• The Heat have hit the over on the total in a higher percentage of home games (51.9%) than away games (50%).
• Against the spread, Memphis has had better results away (13-13-1) than at home (12-15-0).
• Grizzlies games have gone above the over/under more often at home (14 times out of 27) than on the road (11 of 27) this season.

Heat Leaders

• Bam Adebayo is averaging 18.4 points, 9.9 boards and 2.8 assists. Defensively, he averages 1 steal and 0.7 blocked shots.
• Jaime Jaquez Jr. is averaging 15.1 points, 4.7 assists and 5.4 boards.
• Norman Powell is averaging 22.8 points, 2.6 assists and 3.6 boards.
• Andrew Wiggins' numbers on the season are 15.9 points, 5 boards and 2.7 assists per contest, shooting 47% from the field and 39.8% from downtown, with an average of 2 made treys.
• Kel'el Ware's numbers on the season are 11.4 points, 9.3 boards and 0.6 assists per game, shooting 52.7% from the field and 40.3% from beyond the arc, with an average of 1.2 made 3-pointers.

Grizzlies Leaders

• Cam Spencer's numbers on the season are 11.6 points, 2.7 rebounds and 5.7 assists per contest. He is also draining 47.8% of his shots from the floor and 44.8% from beyond the arc (seventh in NBA), with an average of 2.1 triples.
• Per game, Santi Aldama gets the Grizzlies 14 points, 6.7 rebounds and 2.9 assists. He also averages 0.9 steals and 0.7 blocks.
• Jaylen Wells averages 12.1 points, 3.4 boards and 1.7 assists. He is sinking 41.2% of his shots from the field and 33.8% from beyond the arc, with 1.8 treys per contest.
• The Grizzlies receive 6.9 points per game from Walter Clayton Jr., plus 2 rebounds and 3.3 assists.
• GG Jackson's numbers on the season are 9.3 points, 3.6 boards and 1.3 assists per game. He is making 48.5% of his shots from the floor and 33% from 3-point range, with an average of 1 triples.

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