Guardians vs Phillies Prediction, Odds, Moneyline, Spread & Over/Under for May 24

Odds updated as of 9:12 p.m.

The Cleveland Guardians are among the MLB teams in action on Sunday, up against the Philadelphia Phillies.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs Phillies Game Info

• Cleveland Guardians (31-22) vs. Philadelphia Phillies (25-26)
• Date: Sunday, May 24, 2026
• Time: 1:35 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and CleGuardians.TV

Guardians vs Phillies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-124) | PHI: (+106)
• Spread: CLE: -1.5 (+140) | PHI: +1.5 (-170)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Guardians vs Phillies Probable Starting Pitchers

Probable Pitchers: Parker Messick (Guardians) - 5-1, 2.45 ERA vs Andrew Painter (Phillies) - 1-4, 5.77 ERA

The Guardians will look to Parker Messick (5-1) against the Phillies and Andrew Painter (1-4). Messick's team is 7-3-0 against the spread this season in his starts. When Messick starts a game and his team is the favorite on the moneyline, they have a record of 5-2. The Phillies have gone 1-7-0 ATS in Painter's eight starts that had a set spread. The Phillies were named the moneyline underdog for four Painter starts this season -- they lost each time.

Guardians vs Phillies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (55%)

Guardians vs Phillies Moneyline

• The moneyline numbers for Guardians vs. Phillies reveal Cleveland as the favorite (-124) and Philadelphia as the underdog (+106) despite being the home team.

Guardians vs Phillies Spread

• The Guardians are at the Phillies and are favored by 1.5 runs on the spread. The Guardians are +140 to cover the runline, with the Phillies being -170.

Guardians vs Phillies Over/Under

• Guardians versus Phillies, on May 24, has an over/under of 7.5, with the over being -115 and the under -105.

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Guardians vs Phillies Betting Trends

• The Guardians have won in 16, or 59.3%, of the 27 contests they have been named as odds-on favorites in this year.
• This season Cleveland has come away with a win 11 times in 20 chances when named as a favorite of at least -124 on the moneyline.
• Contests with the Guardians have gone over the total set by sportsbooks in 25 of 50 chances this season.
• The Guardians are 27-23-0 against the spread in their 50 games with a line set by sportsbooks this season.
• The Phillies have been the underdog on the moneyline 14 total times this season. They've finished 5-9 in those games.
• Philadelphia is 3-6 (winning just 33.3% of its games) when it has played as a moneyline underdog of +106 or longer.
• In the 51 games oddsmakers have set an over/under for the Phillies, they have combined with opponents to go over the total 24 times (24-25-2).
• The Phillies have covered only 29.4% of their games this season, going 15-36-0 against the spread.

Guardians Player Leaders

• Jose Ramirez has 11 doubles, eight home runs and 37 walks while batting .236. He has an on-base percentage of .359 and a slugging percentage of .415.
• Among qualified hitters in MLB, his batting average ranks 111th, his on-base percentage ranks 40th, and he is 83rd in slugging.
• Ramirez has recorded at least one hit in three straight games. During his last five outings he is batting .300 with two doubles, a home run, two walks and five RBIs.
• Chase DeLauter is batting .266 with 10 doubles, a triple, seven home runs and 24 walks. He's slugging .457 with an on-base percentage of .352.
• He is 56th in batting average, 51st in on-base percentage and 50th in slugging in the majors.
• Brayan Rocchio leads the Guardians with an OPS of .794. He has a slash line of .291/.376/.418 this season.
• Rocchio has recorded at least one base hit in two games in a row. In his last five games he is hitting .357 with two doubles, a triple, three walks and an RBI.
• Angel Martinez leads Cleveland in total hits (41) this season while batting .250 with 18 extra-base hits.

Phillies Player Leaders

• Bryce Harper has a team-high .357 on-base percentage. He's batting .266 and slugging .527.
• Including all qualifying hitters in the majors, he ranks 56th in batting average, 42nd in on-base percentage and 16th in slugging percentage.
• Kyle Schwarber has racked up 41 hits to lead his team. He has a batting average of .225 while slugging .610 with an on-base percentage of .350.
• He is currently 128th in batting average, 56th in on-base percentage and second in slugging percentage among all qualified hitters.
• Brandon Marsh has racked up a slugging percentage of .462, a team-high for the Phillies.
• Trea Turner is hitting .234 with nine doubles, five home runs and 16 walks.

Guardians vs Phillies Head to Head

• 5/22/2026: 1-0 CLE (Favorite: Phillies, Spread: -1.5, Total: 6.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/11/2025: 3-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/10/2025: 7-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/9/2025: 6-0 CLE (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/28/2024: 4-3 CLE (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/27/2024: 8-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/26/2024: 3-1 CLE (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/23/2023: 8-5 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/22/2023: 1-0 CLE (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/21/2023: 6-5 CLE (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)

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