Guardians vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for May 14

Odds updated as of 12:11 a.m.

The MLB schedule on Wednesday includes the Cleveland Guardians facing the Milwaukee Brewers.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs Brewers Game Info

• Cleveland Guardians (25-17) vs. Milwaukee Brewers (20-23)
• Date: Wednesday, May 14, 2025
• Time: 1:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: MLB Network, CLEG, and FDSWI

Guardians vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-154) | MIL: (+130)
• Spread: CLE: -1.5 (+138) | MIL: +1.5 (-166)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Guardians vs Brewers Probable Starting Pitchers

Probable Pitchers: Gavin Williams (Guardians) - 3-2, 4.38 ERA vs Logan Henderson (Brewers) - 0-0, 0.00 ERA

This contest's pitching matchup is set, as the Guardians will send Gavin Williams (3-2) to the mound, while Logan Henderson will take the ball for the Brewers. Williams' team is 5-3-0 against the spread in his starts this season. Williams' team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 2-1. Henderson's team was never a moneyline underdog a season ago in games he pitched.

Guardians vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (50.8%)

Guardians vs Brewers Moneyline

• Cleveland is a -154 favorite on the moneyline, while Milwaukee is a +130 underdog on the road.

Guardians vs Brewers Spread

• The Brewers are at +1.5 on the runline against the Guardians. The Brewers are -166 to cover the spread, and the Guardians are +138.

Guardians vs Brewers Over/Under

• Guardians versus Brewers on May 14 has an over/under of 8.5 runs, with the odds on the over -105 and the under set at -115.

Bet on Cleveland Guardians vs. Milwaukee Brewers on FanDuel today!

Guardians vs Brewers Betting Trends

• The Guardians have been chosen as favorites in 15 games this year and have walked away with the win 11 times (73.3%) in those games.
• Cleveland has not lost in three games when named as a moneyline favorite of -154 or better.
• The Guardians and their opponents have hit the over in 21 of their 41 games with a total set by oddsmakers this season.
• The Guardians are 20-21-0 against the spread in their 41 games with a line set by sportsbooks this season.
• The Brewers have won 20% of the games this season they were the underdog on the moneyline (4-16).
• Milwaukee has not won a game when it entered play as a moneyline underdog with odds of +130 or longer in four chances.
• The Brewers have played in 42 games with an over/under set, and have combined with their opponents to go over the total 16 times (16-25-1).
• The Brewers have put together a 22-20-0 record ATS this season (covering 52.4% of the time).

Guardians Player Leaders

• Steven Kwan leads Cleveland OPS (.853) this season. He has a .333 batting average, an on-base percentage of .392, and a slugging percentage of .461.
• He ranks fifth in batting average, 14th in on-base percentage, and 51st in slugging among qualifying hitters in baseball.
• Kwan has recorded a base hit in three games in a row. In his last five games he is batting .333 with two doubles and two walks.
• Jose Ramirez has 43 hits, which is tops among Cleveland batters this season. He's batting .295 with 15 extra-base hits. He's also slugging .493 with an on-base percentage of .359.
• Among qualified hitters, his batting average places him 23rd, his on-base percentage 44th, and his slugging percentage 28th.
• Ramirez has picked up at least one hit in eight games in a row. In his last 10 games he is hitting .400 with three doubles, two home runs, six walks and four RBIs.
• Kyle Manzardo has collected 28 base hits, an OBP of .313 and a slugging percentage of .484 this season.
• Manzardo has picked up a hit in two straight games. In his last five games he is hitting .263 with a triple, a home run and three RBIs.
• Carlos Santana has been key for Cleveland with 31 hits, an OBP of .327 plus a slugging percentage of .326.

Brewers Player Leaders

• Jackson Chourio has put up a team-high slugging percentage (.470) and paces the Brewers in hits (48). He's batting .265 and with an on-base percentage of .283.
• Including all the qualifying players in MLB, he is 60th in batting average, 129th in on-base percentage and 42nd in slugging percentage.
• Brice Turang is hitting .295 with three doubles, three home runs and 17 walks. He's slugging .376 with an on-base percentage of .367.
• His batting average ranks 23rd among all qualified players, his on-base percentage ranks 37th, and he is 111th in slugging.
• William Contreras is batting .224 with two doubles, four home runs and 24 walks.
• Christian Yelich has four doubles, seven home runs and 20 walks while hitting .205.

Guardians vs Brewers Head to Head

• 5/13/2025: 2-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/12/2025: 5-0 CLE (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/18/2024: 2-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/17/2024: 2-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/16/2024: 5-3 MIL (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/25/2023: 5-4 MIL (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/24/2023: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/23/2023: 7-1 MIL (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!