Dodgers vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 6:12 p.m.

The Los Angeles Dodgers will take on the Baltimore Orioles in MLB action on Friday.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Dodgers vs Orioles Game Info

• Los Angeles Dodgers (78-62) vs. Baltimore Orioles (64-76)
• Date: Friday, September 5, 2025
• Time: 7:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and SportsNet LA

Dodgers vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-166) | BAL: (+140)
• Spread: LAD: -1.5 (-105) | BAL: +1.5 (-114)
• Total: 9 -- Over: (-108) | Under: (-112)

Dodgers vs Orioles Probable Starting Pitchers

Probable Pitchers: Shohei Ohtani (Dodgers) - 1-1, 4.18 ERA vs Dean Kremer (Orioles) - 9-10, 4.52 ERA

The probable starters are Shohei Ohtani (1-1) for the Dodgers and Dean Kremer (9-10) for the Orioles. Ohtani and his team have a record of 4-7-0 against the spread when he starts. Ohtani's team has won 45.5% of his starts when they are favored on the moneyline (5-6). The Orioles have a 13-13-0 record against the spread in Kremer's starts. The Orioles are 5-9 in Kremer's 14 starts this season that they were the moneyline underdog.

Dodgers vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (65.6%)

Dodgers vs Orioles Moneyline

• The Dodgers vs Orioles moneyline has Los Angeles as a -166 favorite, while Baltimore is a +140 underdog at home.

Dodgers vs Orioles Spread

• The Orioles are +1.5 on the spread (-114 to cover), and Los Angeles is -105 to cover the runline.

Dodgers vs Orioles Over/Under

• A combined run total of 9 has been set for Dodgers-Orioles on Sept. 5, with the over at -108 and the under at -112.

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Dodgers vs Orioles Betting Trends

• The Dodgers have won in 69, or 56.6%, of the 122 contests they have been named as odds-on favorites in this year.
• This year Los Angeles has won 41 of 75 games when listed as at least -166 on the moneyline.
• The Dodgers' games have gone over the total in 67 of their 138 opportunities.
• The Dodgers have an against the spread mark of 56-82-0 in 138 games with a line this season.
• The Orioles have put together a 35-42 record in games they were listed as the moneyline underdog (winning 45.5% of those games).
• When it has played as a moneyline underdog with odds of +140 or longer, Baltimore has gone 8-10 (44.4%).
• The Orioles have combined with opponents to hit the over on the total 60 times this season for a 60-73-4 record against the over/under.
• The Orioles have collected a 66-71-0 record against the spread this season (covering 48.2% of the time).

Dodgers Player Leaders

• Ohtani leads Los Angeles in slugging percentage (.606) and total hits (148) this season. He's batting .279 with an on-base percentage of .387.
• Among qualified hitters in MLB, he is 27th in batting average, seventh in on-base percentage, and second in slugging.
• Mookie Betts is batting .250 with 18 doubles, a triple, 15 home runs and 54 walks, while slugging .379 with an on-base percentage of .322.
• Among all qualified hitters, he is 96th in batting average, 92nd in on-base percentage and 130th in slugging percentage.
• Freddie Freeman has collected 139 base hits, an OBP of .368 and a slugging percentage of .489 this season.
• Andy Pages has 24 home runs, 79 RBI and a batting average of .272 this season.

Orioles Player Leaders

• Gunnar Henderson has a team-high OBP (.349) and slugging percentage (.455), while pacing the Orioles in hits (138, while batting .278).
• Including all qualified players in the big leagues, he is 31st in batting average, 44th in on-base percentage and 54th in slugging percentage.
• Jackson Holliday is hitting .249 with 20 doubles, three triples, 16 home runs and 45 walks. He's slugging .391 with an on-base percentage of .315.
• Including all qualifying players, he is 97th in batting average, 107th in on-base percentage and 117th in slugging percentage.
• Ryan Mountcastle has 17 doubles, five home runs and 13 walks while batting .266.
• Colton Cowser is hitting .214 with 12 doubles, 13 home runs and 17 walks.

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