Celtics vs. Lakers Prediction, Odds, Picks, Best Bets for Dec. 5

Celtics vs. Lakers Game Info

• Date: Friday, December 5, 2025
• Time: 7 p.m. ET
• Venue: TD Garden -- Boston, Massachusetts
• Coverage: Amazon Prime Video and SportsNet LA

The Boston Celtics (13-9) will look to Jaylen Brown (fifth in the league scoring 29 points per game) when they attempt to hold off Luka Doncic (first in the NBA with 35.3 PPG) and the Los Angeles Lakers (16-5) on Friday, December 5, 2025 at TD Garden. The Celtics are 8.5-point home favorites in the game, which tips off at 7 p.m. ET on Amazon Prime Video and SportsNet LA. The matchup has an over/under set at 225.5 points.

Celtics vs. Lakers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Celtics vs. Lakers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Celtics win (71%)

Celtics vs. Lakers Betting Trends

• The Celtics have covered the spread 12 times in 22 games with a set spread.
• The Lakers have 14 wins against the spread in 21 games this season.
• Celtics games have gone over the total 10 times out of 21 chances this season.
• The Lakers have eclipsed the over/under 71.4% of the time this season (15 of 21 games with a set point total).
• Boston owns the same winning percentage against the spread in home games (.545) as it does on the road.
• In home games, the Celtics go over the total 54.5% of the time (six of 11 games). They've hit the over in 36.4% of road games (four of 11 contests).
• Los Angeles' winning percentage against the spread at home is .600 (6-4-0). Away, it is .727 (8-3-0).
• Lakers games have finished above the over/under more frequently at home (10 times out of 10) than on the road (five of 11) this season.

Celtics Leaders

• Brown averages 29 points, 6 boards and 4.8 assists.
• Derrick White is averaging 17 points, 4 boards and 5.3 assists. Defensively, he averages 1.6 steals (10th in NBA) and 1.2 blocked shots.
• Payton Pritchard's numbers on the season are 17.3 points, 4.4 boards and 4.9 assists per game, shooting 44.7% from the field and 33.5% from downtown, with an average of 2.7 made 3-pointers.
• Neemias Queta is averaging 10.1 points, 8.2 boards and 1.6 assists. At the other end, he averages 0.6 steals and 1.5 blocked shots (ninth in league).
• Anfernee Simons is averaging 13.7 points, 2.1 rebounds and 2.6 assists.

Lakers Leaders

• Doncic averages 35.3 points for the Lakers, plus 8.9 rebounds and 8.9 assists.
• Per game, Austin Reaves provides the Lakers 28.9 points, 5.7 boards and 6.8 assists. He also averages 1.2 steals and 0.1 blocks.
• Deandre Ayton's numbers on the season are 15.8 points, 8.6 rebounds and 0.9 assists per contest. He is making 71.3% of his shots from the floor (second in NBA).
• Per game, Rui Hachimura gives the Lakers 13.9 points, 3.6 boards and 0.9 assists, plus 0.6 steals and 0.2 blocks.
• Jake Laravia averages 9.2 points, 4 boards and 1.9 assists. He is making 47.4% of his shots from the field and 34.9% from beyond the arc, with 1 treys per game.

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