Cavaliers vs. Knicks Eastern Finals Prediction, Odds, Picks, Best Bets for May 25

Cavaliers vs. Knicks Game Info

• Date: Monday, May 25, 2026
• Time: 8 p.m. ET
• Venue: Rocket Arena -- Cleveland, Ohio
• Coverage: ESPN

The New York Knicks take a 3-0 series lead into a decisive Game 4 of the Eastern Conference Finals. The Knicks are favored by 2.5 points in the matchup, which airs on ESPN at 8 p.m. ET. The point total is set at 217.5 for the matchup.

Cavaliers vs. Knicks Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Cavaliers vs. Knicks Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (57.2%)

Cavaliers vs. Knicks Betting Trends

• The Knicks have covered the spread in a game 42 times this season (42-39-1).
• Against the spread, the Cavaliers are 33-47-2 this year.
• Knicks games have finished with a final combined score above the over/under 37 times this season.
• Cavaliers games this year have hit the over 50% of the time (41 out of 82 games with a set point total).
• When playing at home, New York has a better record against the spread (27-13-0) compared to its ATS record on the road (15-26-1).
• In terms of over/unders, the Knicks hit the over more often when playing at home, as they've exceeded the total 19 times in 40 opportunities this season (47.5%). In away games, they have hit the over 18 times in 42 opportunities (42.9%).
• In 2025-26 against the spread, Cleveland has a better winning percentage at home (.415, 17-23-1 record) than on the road (.390, 16-24-1).
• Cavaliers games have gone above the over/under less often at home (17 times out of 41) than away (24 of 41) this season.

Knicks Leaders

• Jalen Brunson's numbers on the season are 26 points, 3.3 rebounds and 6.8 assists per contest, shooting 46.7% from the floor and 36.9% from downtown, with an average of 2.6 made treys.
• Karl-Anthony Towns is averaging 20.1 points, 3 assists and 11.9 rebounds.
• Mikal Bridges averages 14.4 points, 3.8 boards and 3.7 assists.
• OG Anunoby averages 16.7 points, 5.2 rebounds and 2.2 assists, shooting 48.4% from the floor and 38.6% from beyond the arc, with 2.3 made treys per contest.
• Josh Hart is averaging 12 points, 4.8 assists and 7.4 rebounds.

Cavaliers Leaders

• Donovan Mitchell's numbers on the season are 27.9 points, 4.5 rebounds and 5.7 assists per game. He is also sinking 48.3% of his shots from the floor and 36.4% from beyond the arc, with an average of 3.2 triples (sixth in league).
• James Harden's numbers on the season are 23.6 points, 4.8 rebounds and 8 assists per contest. He is sinking 43.4% of his shots from the floor and 37.5% from 3-point range, with an average of 3.1 triples (ninth in league).
• Per game, Evan Mobley gives the Cavaliers 18.2 points, 9 rebounds and 3.6 assists, plus 0.7 steals and 1.7 blocks (fourth in NBA).
• Per game, Jarrett Allen provides the Cavaliers 15.4 points, 8.5 boards and 1.8 assists, plus 1 steal and 0.8 blocks.
• Jaylon Tyson's numbers on the season are 13.2 points, 5.1 boards and 2.2 assists per game. He is sinking 49.3% of his shots from the floor and 44.6% from beyond the arc (fourth in league), with an average of 2 triples.

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