Cardinals vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for March 28

Odds updated as of 10:12 p.m.

On Saturday in MLB, the St. Louis Cardinals are up against the Tampa Bay Rays.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cardinals vs Rays Game Info

• St. Louis Cardinals (1-0) vs. Tampa Bay Rays (0-1)
• Date: Saturday, March 28, 2026
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and Rays.TV

Cardinals vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-112) | TB: (-104)
• Spread: STL: +1.5 (-210) | TB: -1.5 (+172)
• Total: 7.5 -- Over: (+100) | Under: (-122)

Cardinals vs Rays Probable Starting Pitchers

Probable Pitchers: Michael McGreevy (Cardinals) - 0-0, 0.00 ERA vs Joe Boyle (Rays) - 0-0, 0.00 ERA

The Cardinals will call on Michael McGreevy against the Rays and Joe Boyle. McGreevy and his team were 9-7-0 against the spread when he pitched last season. McGreevy and his team won as favorites in 50% of his six appearances last season with a moneyline. Last season Boyle and his team went 3-6-0 against the spread in games he pitched. Boyle and his team put together a 3-6 record in the nine games he pitched when they were the moneyline underdog a season ago.

Cardinals vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (50.7%)

Cardinals vs Rays Moneyline

• St. Louis is a -112 favorite on the moneyline, while Tampa Bay is a -104 underdog on the road.

Cardinals vs Rays Spread

• The Rays are 1.5-run favorites against the spread for this matchup with the Cardinals. The Rays are +172 to cover, while the Cardinals are -210 to cover as a 1.5-run underdog on the runline.

Cardinals vs Rays Over/Under

• A combined run total of 7.5 has been set for Cardinals-Rays on March 28, with the over at +100 and the under at -122.

Bet on St. Louis Cardinals vs. Tampa Bay Rays on FanDuel today!

Cardinals vs Rays Betting Trends

• The Cardinals came away with 32 wins in the 65 contests they were listed as the favorites last season.
• Last season St. Louis came away with a win 30 times in 61 chances when named as a favorite of at least -112 or shorter on the moneyline.
• The Cardinals and their opponents hit the over in 80 of their 156 games with a total last season.
• The Rays won 40.5% of the games last season they were the moneyline underdog (32-47).
• Tampa Bay went 29-41 when it played as a moneyline underdog with odds of -104 or longer (41.4%).
• The Rays combined with their opponents to hit the over on the total 69 times last season for a 69-79-9 record against the over/under.

Cardinals Player Leaders

• Alec Burleson collected 144 hits, posted an OBP of .343 and a .459 SLG last season.
• Ivan Herrera slashed .284/.373/.464 and finished with an OPS of .837.
• Masyn Winn ended his last campaign with 124 hits, an OBP of .310, plus a slugging percentage of .363.
• Victor Scott II slashed .216/.305/.296 and finished with an OPS of .601.

Rays Player Leaders

• Junior Caminero had 159 hits and a batting average of .264 a season ago.
• Yandy Diaz had an OBP of .366 and slugged .482.
• Chandler Simpson had 15 doubles, three triples and 20 walks while batting .295 last season.
• Cedric Mullins hit .216 with 23 doubles, a triple, 17 home runs and 50 walks.

Cardinals vs Rays Head to Head

• 3/26/2026: 9-7 STL (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/22/2025: 10-6 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/21/2025: 7-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/8/2024: 6-4 TB (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/7/2024: 5-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/6/2024: 4-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/10/2023: 5-2 STL (Favorite: Rays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 8/9/2023: 6-4 STL (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/8/2023: 4-2 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/9/2022: 2-1 TB (Favorite: Rays, Spread: -1.5, Total: 6.5, Favorite Moneyline: -168, Underdog Moneyline: +142)

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