Bulls vs. Pistons Prediction, Odds, Picks, Best Bets for Feb. 21

Bulls vs. Pistons Game Info

• Date: Saturday, February 21, 2026
• Time: 8 p.m. ET
• Venue: United Center -- Chicago, Illinois
• Coverage: CHSN and FDSDET

The Detroit Pistons (41-13) are heavy, 10.5-point favorites as they try to continue a four-game winning streak when they visit the Chicago Bulls (24-32) on Saturday, February 21, 2026 at United Center. The contest airs at 8 p.m. ET on CHSN and FDSDET. The matchup has an over/under of 234.5.

Bulls vs. Pistons Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Bulls vs. Pistons Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Pistons win (74.2%)

Bulls vs. Pistons Betting Trends

• The Pistons have put together a record of 30-23-1 against the spread this season.
• In the Bulls' 56 games this year, they have 24 wins against the spread.
• This season, 24 of the Pistons' games have gone over the point total out of 56 chances.
• Bulls games this season have eclipsed the over/under 50% of the time (28 out of 56 games with a set point total).
• Against the spread, Detroit has played worse when playing at home, covering 15 times in 28 home games, and 15 times in 26 road games.
• The Pistons have eclipsed the over/under in a lower percentage of home games (42.9%) than games on the road (46.2%).
• Against the spread, Chicago has performed better at home (13-14-1) than on the road (11-17-0).
• Looking at the over/under, Bulls games have finished over less frequently at home (12 of 28, 42.9%) than on the road (16 of 28, 57.1%).

Pistons Leaders

• Cade Cunningham's numbers on the season are 25.7 points, 5.7 rebounds and 9.7 assists per game, shooting 46.3% from the field and 33.5% from downtown, with an average of 2 made 3-pointers.
• Jalen Duren's numbers on the season are 17.7 points, 10.4 boards and 1.8 assists per contest, shooting 63.1% from the floor (sixth in league).
• Ausar Thompson's numbers on the season are 10.2 points, 6 rebounds and 2.7 assists per contest, shooting 51.1% from the field.
• Duncan Robinson is averaging 12.2 points, 1.8 assists and 2.7 boards.
• Kevin Huerter is averaging 10.3 points, 2.5 assists and 3.7 boards.

Bulls Leaders

• Matas Buzelis averages 15 points, 5.4 boards and 2.1 assists. He is also draining 47% of his shots from the floor and 36.3% from 3-point range, with 2 triples per contest.
• The Bulls get 18.2 points per game from Josh Giddey, plus 8.5 boards and 8.7 assists.
• The Bulls get 14.5 points per game from Anfernee Simons, plus 2.5 rebounds and 2.5 assists.
• Tre Jones averages 12.4 points, 2.9 boards and 5.8 assists. He is making 55.2% of his shots from the field.
• The Bulls are receiving 14.3 points, 2 rebounds and 3.6 assists per game from Collin Sexton.

For more NBA betting insights, check out FanDuel Research's NBA home page.

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