Brock Purdy Fantasy Football Week 16: Stats and Projections vs. Colts

In Week 16 (Monday at 8:15 p.m. ET), QB Brock Purdy and the San Francisco 49ers will meet the Indianapolis Colts, who have the 30th-ranked passing defense in the league (247.6 yards allowed per game).

Considering Purdy for your DFS roster, with his next game against the Colts? We've got stats and info for you in this article.

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Brock Purdy Week 16 Fantasy Football Projection

• Matchup: San Francisco 49ers at Indianapolis Colts
• Game Date: December 22, 2025
• Game Time: 8:15 p.m.
• Projected Fantasy Points: 18.3
• Projected Passing Yards: 256.78
• Projected Passing TDs: 1.84
• Projected Rushing Yards: 16.48
• Projected Rushing TDs: 0.18

Projections provided by numberFire

Purdy Fantasy Performance

• With 104.4 fantasy points in 2025 (17.4 per game), Purdy is the 33rd-ranked player at the QB position and 122nd among all players.
• During his last three games, Purdy has piled up 656 passing yards (62-of-91) for five passing TDs with three picks, leading to 50.6 fantasy points (16.9 per game) during that period. On the ground, he's contributed 64 yards rushing on 15 carries with one touchdown.
• Purdy has accumulated 1,165 passing yards (103-of-155) with 10 TDs and five picks in his last five games, leading to 87.6 fantasy points (17.5 per game) during that stretch. On the ground, he's contributed 70 yards rushing on 18 carries with one touchdown.
• The highlight of Purdy's fantasy season so far was last week against the Tennessee Titans, when he caught zero balls on targets for zero yards, good for 26.2 fantasy points.
• From a fantasy perspective, Brock Purdy stumbled to his worst performance of the season in Week 12 against the Carolina Panthers, throwing for 193 yards and one touchdown with three interceptions with 16 yards on six attempts on the ground (7.3 fantasy points).

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Colts Defensive Performance

• Indianapolis has given up more than 300 yards passing to four players this season.
• The Colts have allowed 10 players to pass for at least one TD in a game this year.
• Indianapolis has allowed five players to pass for at least two touchdowns in a game this year.
• Three players have passed for at least three TDs in a game versus the Colts this year.
• A total of six players have collected more than 100 yards receiving in a game versus Indianapolis this season.
• A total of 18 players have hauled in a touchdown pass versus the Colts this year.
• Indianapolis has not allowed an opposing player to catch more than one touchdown pass in a game this season.
• One player has picked up over 100 yards rushing in a game versus the Colts this year.
• Indianapolis has allowed at least one rushing touchdown to 10 players this season.
• A total of Three players have rushed for more than one TD against the Colts this year.

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