Bills vs Patriots Prediction, Odds, Picks, Best Bets for NFL Week 15

The Buffalo Bills are among the NFL teams playing on Sunday, up against the New England Patriots.
All the information you need is below, in order to make a smart bet on this game at FanDuel Sportsbook.
Bills vs Patriots Prediction & Pick
All NFL win probability predictions and picks are according to numberFire.
Prediction: Patriots win (52.3%)
Bills vs Patriots Point Spread
The Bills are 1.5-point favorites against the Patriots. The Bills are -115 to cover the spread, while the Patriots are -105 to cover as a 1.5-point underdog.
Bills vs Patriots Over/Under
A total of 48.5 points has been set for the Bills-Patriots matchup on Dec. 14, with the over available at -115 and the under at -105.
Bills vs Patriots Moneyline
Looking at the moneyline for Bills-Patriots, Buffalo is the favorite at -126, and New England is +108 playing at home.
Bills vs Patriots Betting Trends
- Buffalo's record against the spread is 6-7-0.
- Against the spread as 1.5-point favorites or more, the Bills are 4-7.
- This year, six of the Bills' 13 games have hit the over.
- The Patriots are 9-4-0 against the spread this season.
- New England's ATS record as 1.5-point underdogs or more is 3-1.
- This season, seven of the Patriots' 13 games have hit the over.
Check out even more in-depth Bills vs. Patriots analysis on FanDuel Research.
Bills vs Patriots Odds & Spread
- All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: BUF: (-126) | NE: (+108)
- Spread: BUF: -1.5 (-115) | NE: +1.5 (-105)
- Total: 48.5 -- Over: (-115) | Under: (-105)
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