NFL
Bills vs Chiefs NFL Odds, Predictions, Spread, Kickoff Time & Best Bets for AFC Divisional Round - January 21
![Bills vs Chiefs NFL Odds, Predictions, Spread, Kickoff Time & Best Bets for AFC Divisional Round - January 21](/research/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2Fpbwem9y5%2Fch_production%2F6c20c50353ee03921394cfab2e51182ea36f965c-3949x2633.jpg%3Frect%3D0%2C340%2C3949%2C1954%26w%3D964%26h%3D477&w=1920&q=100)
NFL action on Sunday includes the Buffalo Bills taking on the Kansas City Chiefs.
Get the latest NFL odds ahead of this matchup on FanDuel Sportsbook.
Bills vs Chiefs Prediction & Pick
All NFL win probability predictions and picks are according to numberFire.
Prediction: Bills win (66.8%)
Bills vs Chiefs Point Spread
The Bills are 2.5-point favorites against the Chiefs. The Bills are -115 to cover the spread, while the Chiefs are -105 to cover as a 2.5-point underdog.
Bills vs Chiefs Over/Under
The Bills-Chiefs matchup on January 21 has been given an over/under of 45.5 points. The over is -115 and the under is -105.
Bills vs Chiefs Moneyline
Kansas City is the underdog, +128 on the moneyline, while Buffalo is a -152 favorite at home.
Bills vs Chiefs Betting Trends
- Buffalo was 7-10-0 against the spread during the season. It holds an ATS record of 1-0-0 in the playoffs.
- Against the spread as 2.5-point favorites or more, the Bills are 7-8 (in the regular season and playoffs).
- In the regular season, six of the Bills' 17 games hit the over. They are one of one in terms of exceeding the over/under in the postseason.
- Against the spread, the Chiefs were 10-7-0 during the regular season and are 1-0-0 in the playoffs.
- Kansas City is unbeaten ATS (1-0) as a 2.5-point underdog or more in the regular season and playoffs.
- There were five Chiefs games (out of 17) that hit the over in the regular season, and zero (of one) in the playoffs.
Bills vs Chiefs Odds & Spread
- All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: BUF: (-152) | KC: (+128)
- Spread: BUF: -2.5 (-115) | KC: +2.5 (-105)
- Total: 45.5 -- Over: (-115) | Under: (-105)