Alabama vs Oklahoma Prediction, Odds, Picks, Best Bets for 2025 CFP First Round

On Friday in college football, the Oklahoma Sooners are up against the Alabama Crimson Tide.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Oklahoma vs Alabama Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Oklahoma: (-112) | Alabama: (-104)
• Spread: Oklahoma: -1.5 (-104) | Alabama: +1.5 (-118)
• Total: 40.5 -- Over: (-105) | Under: (-115)

Oklahoma vs Alabama Betting Trends

• Oklahoma is 7-5-0 against the spread this year.
• Oklahoma's ATS record as 1.5-point or bigger favorites is 5-4.
• Two of 12 Oklahoma games have hit the over this season.
• Alabama has eight wins in 13 contests against the spread this year.
• Alabama has one win ATS (1-1) as a 1.5-point underdog or greater this year.
• Alabama has seen four of its 13 games hit the over.

Oklahoma vs Alabama Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Sooners win (53.1%)

Oklahoma vs Alabama Point Spread

Oklahoma is favored by 1.5 points against Alabama. Oklahoma is -104 to cover the spread, while Alabama is -118.

Oklahoma vs Alabama Over/Under

A total of 40.5 points has been set for the Oklahoma-Alabama game on Dec. 19, with the over available at -105 and the under at -115.

Oklahoma vs Alabama Moneyline

Oklahoma is a -112 favorite on the moneyline, while Alabama is a -104 underdog.

Oklahoma vs. Alabama Points Insights

Oklahoma vs. Alabama Game Info

• Game day: Friday, December 19, 2025
• Game time: 8 p.m. ET
• TV channel: ABC
• Location: Norman, Oklahoma
• Stadium: Gaylord Family Oklahoma Memorial Stadium

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Check out even more in-depth Oklahoma vs. Alabama analysis on FanDuel Research.