49ers vs Titans Prediction, Odds, Picks, Best Bets for NFL Week 15

The Sunday schedule in the NFL includes a matchup between the San Francisco 49ers and the Tennessee Titans.

Get the latest NFL odds ahead of this matchup on FanDuel Sportsbook.

49ers vs Titans Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction:

49ers vs Titans Point Spread

The 49ers are 12.5-point favorites against the Titans. The 49ers are -115 to cover the spread, while the Titans are -105 to cover as a 12.5-point underdog.

49ers vs Titans Over/Under

An over/under of 44.5 has been set for 49ers-Titans on Dec. 14, with the over being -105 and the under -115.

49ers vs Titans Moneyline

San Francisco is a -952 favorite on the moneyline, while Tennessee is a +640 underdog on the road.

49ers vs Titans Betting Trends

• San Francisco has eight wins in 13 games against the spread this year.
• Out of 13 49ers games so far this season, seven have hit the over.
• The Titans have six wins in 13 contests against the spread this season.
• As a 12.5-point underdog or greater, Tennessee has one win ATS (1-1) this season.
• Out of 13 Titans games so far this year, eight have hit the over.

Check out even more in-depth 49ers vs. Titans analysis on FanDuel Research.

49ers vs Titans Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-952) | TEN: (+640)
• Spread: SF: -12.5 (-115) | TEN: +12.5 (-105)
• Total: 44.5 -- Over: (-105) | Under: (-115)

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