49ers vs Titans Prediction, Odds, Picks, Best Bets for NFL Week 15

NFL action on Sunday includes the San Francisco 49ers facing the Tennessee Titans.

Get the latest NFL odds ahead of this matchup on FanDuel Sportsbook.

49ers vs Titans Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: 49ers win (89.8%)

49ers vs Titans Point Spread

The 49ers are 12.5-point favorites against the Titans. The 49ers are -112 to cover the spread, while the Titans are -108 to cover as a 12.5-point underdog.

49ers vs Titans Over/Under

The over/under for 49ers-Titans on Dec. 14 is 44.5. The over is -108, and the under is -112.

49ers vs Titans Moneyline

Looking at the moneyline for 49ers-Titans, San Francisco is the favorite at -952, and Tennessee is +640 playing on the road.

49ers vs Titans Betting Trends

• San Francisco has beaten the spread eight times in 13 games.
• Out of 13 49ers games so far this year, seven have hit the over.
• The Titans have covered the spread six times in 13 games.
• Tennessee has won once ATS (1-1) as a 12.5-point underdog or more this season.
• The Titans have played 13 games this year, and eight of them have gone over the total.

Check out even more in-depth 49ers vs. Titans analysis on FanDuel Research.

49ers vs Titans Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-952) | TEN: (+640)
• Spread: SF: -12.5 (-112) | TEN: +12.5 (-108)
• Total: 44.5 -- Over: (-108) | Under: (-112)

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